Translating Research into Highest Quality Patient Care

DSRB - Introduction


The Domain Specific Review Board (DSRB)


The NHG Domain Specific Review Board (DSRB) is an independent committee constituted of medical, scientific and nonscientific members, whose responsibility is to ensure the protection of the rights, safety, and well-being of human subjects involved in a research study by, among other things, reviewing, approving, and providing continuing review of research studies, of protocols and amendments, and of the methods and materials to be used in obtaining and documenting informed consent of the research subjects.

The DSRB is empowered under the auspices of the NHG Chairmen Medical Boards Committee, whose authority applies to all research involving patients, staff, premises, or facilities of NHG institutions and all other institutions under its oversight. Other officials of institutions which conduct research under the oversight of NHG DSRB, may not override the decision of DSRB (or REC, where applicable).


The Six Domains
There are currently five Biomedical Domains (A-E) that are based on broad but related disease groupings and a Population Health Domain (F). Each Board is made up of 11-15 members and constituted in compliance with the Singapore Guideline for Good Clinical Practice.

The characteristic of such an arrangement is to ensure that more appropriate expertise can be concentrated within each Domain to assess the scientific and ethical merits of the protocols submitted for ethics review.

The specialties under DSRB are as follows (as of 02 November 2012):


NOTE: For Allied Health, Nursing & Para-clinical research protocols, please select the most appropriate Domain according to the main disease type/condition being studied. Do note that the DSRB may re-assign your application to another Domain upon preliminary review of your application.


 

Domain B – Two Independent Boards (as of 01 February 2011)

Over the years, the volume of research studies submitted to the DSRB has increased significantly. This trend is especially evident for oncology-related clinical research and clinical trials submitted to Domain B.


In order to maintain the high quality of review and ethics oversight, as well as to expand the capabilities of the DSRB to manage the increase effectively, it is necessary for the formation of two independent Boards to oversee the research studies submitted to Domain B. Each Board comprises its own Chairperson and Committee Members and will hold separate meetings every month. The decisions made by each Board will be recognized by the other DSRBs, therefore Investigators will not be allowed to submit the same ethics application more than once.


With effect from 01 February 2011, all new and existing studies under the oversight of Domain B will be triaged to either Domain B Board 1 or Board 2. This will be done by the Domain B Secretariat and Investigators will be notified accordingly. There will be no change to the submission process as Investigators need only indicate that his/her ethics application is submitted to Domain B.

Please contact the Domain B Secretariat if you have further queries.



DSRB Meeting Dates for 2014


Domains

A

B1

B2

C

D

E

F1

F2

Jan

13 Jan 14

14 Jan 14

28 Jan 14

21 Jan 14

30 Jan 14

29 Jan 14

14 Jan 14

15 Jan 14

Feb

17 Feb 14

18 Feb 14

25 Feb 14

25 Feb 14

27 Feb 14

26 Feb 14

11 Feb 14

12 Feb 14

Mar

17 Mar 14

18 Mar 14

25 Mar 14

19 Mar 14

27 Mar 14

26 Mar 14

11 Mar 14

12 Mar 14

Apr

14 Apr 14

15 Apr 14

29 Apr 14

29 Apr 14

24 Apr 14

23 Apr 14

8 Apr 14

9 Apr 14

May

19 May 14

20 May 14

27 May 14

27 May 14

29 May 14

28 May 14

13 May 14

14 May 14

Jun

16 Jun 14

17 Jun 14

24 Jun 14

24 Jun 14

26 Jun 14

25 Jun 14

10 Jun 14

11 Jun 14

Jul

14 Jul 14

15 Jul 14

29 Jul 14

29 Jul 14

31 Jul 14

23 Jul 14

8 Jul 14

9 Jul 14

Aug

18 Aug 14

12 Aug 14

26 Aug 14

26 Aug 14

28 Aug 14

27 Aug 14

12 Aug 14

13 Aug 14

Sep

15 Sep 14

16 Sep 14

23 Sep 14

30 Sep 14

25 Sept 14

24 Sep 14

9 Sep 14

10 Sep 14

Oct

13 Oct 14

14 Oct 14

28 Oct 14

28 Oct 14

30 Oct 14

29 Oct 14

14 Oct 14

15 Oct 14

Nov

17 Nov 14

18 Nov 14

25 Nov 14

25 Nov 14

27 Nov 14

26 Nov 14

11 Nov 14

12 Nov 14

Dec

-

-

-

-

-

-

-

-

















Please note that the above timetable is correct as of 30 Dec 2013 and may be subject to change without prior notice.

The above timetable is only for information. Investigators must follow the following deadlines for the submissions to be reviewed accordingly.


Full Board Study Application

  • The submission deadline for new studies requiring full board review is the 1st working day of each calendar month.

  • Studies received by this deadline will be reviewed within the same calendar month*. For example, applications to be reviewed at the meeting in July 2013 must reach DSRB by 1 July 2013.

  • The PI should submit with sufficient lead time for the Department Representative and Institutional Representative to endorse prior to the 1st working day of the month.
  • Submissions received after the 1st working day would be tabled for the subsequent full board meeting.

Full Board Study Amendments

  • Similarly, the deadline for any study amendments (page 44) that require full board review by the DSRB is the 1st working day of each calendar month.*

Exempt and Expedited studies

  • There is no specific deadline for new studies that qualify for exempt (page 63) or expedited (page 66) review. Studies that do not qualify for exempt or expedited review will require full board review by the DSRB.

All new completed applications accepted by the DSRB will be reviewed within thirty calendar days**. However, the time frame from submission to approval will vary depending on factors such as the completeness of the application, complexity of the study, and the response of the Investigator to DSRB's queries.

The DSRB Full Board meeting dates can be downloaded here.

For any further queries, please feel free to contact the DSRB listed below.


* Except in December

** Subject to availability of a meeting quorum





NHG Domain Specific Review Board (DSRB) Contact List

 

 

 

 

Asst Director of OHRPP

Ms NG HWEE HIAN

6496 6017

hwee_hian_ng@nhg.com.sg

Asst Manager of DSRB

Ms FELICIA WONG

6496 6983

felicia_yx_wong@nhg.com.sg

Lead IRB Analyst

Ms LEONG YUAN TING

6496 6955

yuan_ting_leong@nhg.com.sg

 

Domain A

IRB Analyst

Ms QIU SHIJIA 

6496 6954

shijia_qiu@nhg.com.sg

IRB Analyst

Ms TEO YI LING

6340 2410

yi_ling_teo@nhg.com.sg

Asst IRB Analyst

Ms GUO QIANPING

6496 6956

qianping_guo@nhg.com.sg

Asst IRB Analyst

Ms NURLATIFAH BINTE RAZALI

6340 2408

nurlatifah_razali@nhg.com.sg

 

Domain B1

IRB Analyst

Ms JEAN FOO

6496 6958

jean_cy_foo@nhg.com.sg

Asst IRB Analyst

Ms JAYLYNN CHONG

6496 6957

jaylynn_xj_chong@nhg.com.sg

 

 

 

 

Domain B2

IRB Analyst

Ms NORSALLEHA BINTE SALIM

6496 6960

norsalleha_bte_salim@nhg.com.sg

Snr Asst IRB Analyst

Mr EDWIN HONG

6496 6978

edwin_jq_hong@nhg.com.sg

 

 

 

 

Domain C

IRB Analyst

Ms AMBER LIM

6496 6910

amber_sq_lim@nhg.com.sg

Asst IRB Analyst

Ms NURUL HUDA BINTE RAHMAT

6496 6906

huda_rahmat@nhg.com.sg

 

Domain D

IRB Analyst

Ms SIA SU GHIM

6496 6953

su_ghim_sia@nhg.com.sg

Asst IRB Analyst

Ms NUR FARZIRA HAIRUDIN         

6496 6959

nur_farzira_hairudin@nhg.com.sg

 

Domain E

IRB Analyst

Ms JULIA NG

6496 6258

julia_sy_ng@nhg.com.sg

IRB Analyst

Ms ZHANG CAILIAN

6340 2412

cailian_zhang@nhg.com.sg

Asst IRB Analyst

Ms TAN CHUN YUE

6496 6986

chun_yue_tan@nhg.com.sg

 

Domain F

IRB Analyst

Ms ELING HO

6496 6912

eling_ll_ho@nhg.com.sg

Asst IRB Analyst

Ms GAIYATHRI D/O ELANKOVAN

6496 6964

gaiyathri_elankovan@nhg.com.sg

 

 

 

 



Download DSRB Contact List
 

Domain Specific Review Board (DSRB)

c/o National Healthcare Group, Research & Development Office (RDO)
Nexus @One-North (South Tower), No. 3 Fusionopolis Link, #03-08, Singapore 138543

T : (65) 6471 3266; F : (65) 6496 6257

E: OHRPP@nhg.com.sg


Correct as of  6 March 2014



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